The American Sugar Refining Company (ASR) was the most significant American business unit in the sugar refining industry in the early 1900s. It had interests in Puerto Rico and other Caribbean locations and operated one of the world's largest sugar refineries, the Domino Sugar Refinery in Brooklyn, New York.
The company subsequently acquired five additional sugar refineries and changed the official name to "Domino Sugar" in 1900. The name change was officially recognized by the patent office on October 8, 1901.