Dayr az-Zawr > Doura-Europos Dayr az-Zawr Syria
260 CE
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The Great Crossroads
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Seleucus founds the city of Europos on the Euphrates River in Syria in 303 BCE.
The new city controls the river crossing on the route between his newly founded cities of Antioch and Seleucia on the Tigris.
…attacks Mesopotamia, and …
...Doura-Europus, on the middle Euphrates, is likewise falling to the Persian assault, opening Anatolia and Armenia to Persian invasion.
Emperor Valerian, who has taken charge of the empire's eastern frontiers, rushes to the aid of Doura-Europus, but he cannot remedy the situation.
The city, destroyed in the Persian siege, is abandoned completely.
Later in 259, ...
...Rome’s eastern boundary is pushed back to the Euphrates.