Christopher Myngs himself had been severely wounded during the pirate attack on Campeche Bay, and in 1664 had returned to England to recover.

He had in 1665 been made Vice-Admiral in Prince Rupert's squadron.

As Vice-Admiral of the White under the Lord High Admiral James Stewart, Duke of York and Albany, he had flown his flag during the Second Anglo-Dutch War at the Battle of Lowestoft in 1665, and for his share in that action has received the honor of knighthood.

He subsequently served in the same year under Edward Montagu, 1st Earl of Sandwich, as Vice-Admiral of the Blue and after the disgrace of Montagu under the next supreme fleet commander, George Monck, 1st Duke of Albemarle.

He was on detachment with Prince Rupert's Green squadron when the great Four Days' Battle began, but returned to the main fleet in time to take part on the final day, and in this action when his flotilla was surrounded by that of Vice-Admiral Johan de Liefde he had received a wound—being hit first through the cheek and then in the left shoulder by musket balls fired by a sharpshooter when his Victory was challenged by De Liefde's flagship, the Ridderschap van Holland—of which he dies shortly after returning to London.