Hua Tuo pioneers the use of anesthesia …

Years: 208 - 208
Hua Tuo pioneers the use of anesthesia and performs abdominal surgery, including spleen removal.

Cao Cao, later to be famous as the tyrannical founder of the Cao Wei kingdom, is Hua Tuo's best-known patient, and suffers from chronic headaches (possibly caused by a brain tumor).

Cao has ordered Hua to work as his personal physician, which Hua resents.

In order to avoid treating Cao, Hua repeatedly makes excuses that his wife is ill, but Cao discovers the deception and orders Hua's execution.

Xun Yu, an advisor of Cao Cao, petitions on behalf of the physician.

Hua Tuo writes down his medical techniques while awaiting execution, but destroys his Qingnang shu (lit."green bag book", which becomes a Classical Chinese term for "medical practices text").

This loss to traditional Chinese medicine is irreplaceable.

Cao Cao later regrets executing Hua when his son Cao Chong (196-208), a child prodigy who discovered Archimedes' principle, dies from illness.

The Sanguozhi does not specify Hua Tuo's exact date of death, but since Cao Chong dies in 208, Hua Tuo could not have lived past this year.

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