The Dzungar genocide is the mass extermination of the Buddhist Dzungar people, sometimes referred as "Zunghars", at the hands of the Manchu Qing dynasty of China and the Uyghur Muslims of Xinjiang.

The Qianlong Emperor orders the genocide due to the Dzungar leader Amursana's rebellion against Qing rule after the dynasty first conquered the Dzungar Khanate with Amursana's support before he rebelled in 1755.

The genocide is perpetrated by Manchu generals of the Qing army sent to crush the Dzungars, supported by allies and vassals like Uyghur leader Khoja Emin due to the Uyghurs revolt against Dzungar rule.

The Dzungars are a confederation of several Tibetan Buddhist Oirat tribes that had emerged suddenly in the early seventeenth century.

The Dzungar Khanate is the last great nomadic empire in Asia.

Some scholars estimate that about eighty percent of the Dzungar population, or around five hundred thousand to eight hundred thousand people, are killed by a combination of warfare and disease during or after the Qing conquest in 1755–1757.

After wiping out the native population of Dzungaria, the Qing government then resettles Han Chinese, Hui, Uyghur, and Xibe people on state farms in Dzungaria along with Manchu Bannermen to repopulate the area.