The Ottoman invasion of Otranto occurs between 1480 and 1481 at the Italian city of Otranto in Apulia, southern Italy.

Forces of the Ottoman Empire invade and lay siege to the city and its citadel.

After capture, more than eight hundred of its inhabitants—who refuse to convert to Islam—are executed.

The Martyrs of Otranto are still celebrated in Italy.

A year later the Ottoman garrison surrenders the city following a siege by Christian forces.