Ephesus had revolted after the treacherous death…

Ephesus had revolted after the treacherous death of Agathocles, giving the Hellenistic king of Syria and Mesopotamia Seleucus I Nicator in 281 BCE an opportunity for removing and killing Lysimachus, his last rival, at the Battle of Corupedium.

The town again is named Ephesus after the death of Lysimachus, and thus becomes part of the Seleucid Empire.