Mausolus has made Halicarnassus the metropolis of…

The Persians burn Sidon in 351 BCE following a revolt against Achaemenid rule.

Artaxerxes, a cruel but energetic ruler, attempts to subjugate Egypt, which has been independent since 404.

Failure in 351 of the first attempt encourages ...

...a revolt of the Phoenician towns and ...

...the princes of Cyprus.

Philip had turned aside to the coast of Thrace, avoiding a direct confrontation with Athens, but his intentions were clear.

Many Athenians, however, continue to believe that Philip's threat was transitory, though not Demosthenes, who in the first half of 351 denounces Philip and Macedonian imperialism in his “First Philippic.” He decries the Athenian moves to counter Philip as always being too little and coming too late, and urges the creation of a task force and larger emergency force.

He reminds the Athenians that they had once defeated the Spartans, who were as strong as Philip, and sarcastically points out that Philip would never have conquered their territories if he were as timid as the Athenians seem to be.

He concludes by challenging his countrymen to take their affairs in their own hands rather than let Philip win by default.

It is not clear how influential Demosthenes' advice is—or how influential, at this stage, it deserves to be: at about the same time, and perhaps actually after the First Philippic, Demosthenes is found advocating, in the Speech on the Freedom of the Rhodians, a foolish diversion of resources to the southeastern Aegean against the encroachments of Mausolus' family.

The situation there is, in fact, beyond repair.

The goading First Philippic fails to rouse the Athenians but they do send a small contingent in September 351 when Philip lays siege to a place called Heraeum Teichos.

Tarquinia wins a truce from Rome in 351 BCE, then allies with Sutri.

The Ionian city of Priene had originally been situated along the mouth of the Maeander River but in about 350 BCE the citizens build a new city farther inland on the present site (near present Turunclar, Turkey), laying the streets on a grid plan at the foot of a spectacular cliff.

Phocis retains control of Delphi and continues the building of the temple, although other Greeks express their resentment at the lavish display of valuable ornaments on Phocian women at the Pythian games of 350 BCE.

Philip invades Molossia in 350 BCE and installs his brother-in-law Alexander as king.

Arybbas flees to Athens (where he will die peacefully in 342 BCE).

Phayllus, after serving two years as war archon of Phocis, dies of illness and is succeeded by his nephew Phalaecus, Onomarchus' son, …