Nearly all of Babylon opposed the Achaemenids …

Years: 333BCE - 190BCE

Nearly all of Babylon opposed the Achaemenids by the fourth century BCE.

Thus, when the Iranian forces stationed in Babylon surrender to Alexander the Great of Macedon in 331 BCE, all of Babylonia hails him as a liberator.

Alexander quickly wins Babylonian favor when, unlike the Achaemenids, he displays respect for such Babylonian traditions as the worship of their chief god, Marduk.

Alexander also proposes ambitious schemes for Babylon.

He plans to establish one of the two seats of his empire here and to make the Euphrates navigable all the way to the Persian Gulf, where he plans to build a great port.

Alexander's grandiose plans, however, never come to fruition.

Returning from an expedition to the Indus River, he dies in Babylon—most probably from malaria contracted there in 323 BCE—at the age of thirty-two.

His generals fight for and divide up his empire in the politically chaotic period after Alexander's death.

Many of the battles among the Greek generals are fought on Babylonian soil.

Greek military campaigns in the latter half of the Greek period are focused on conquering Phoenician ports and Babylonia is thus removed from the sphere of action.

The city of Babylon loses its preeminence as the center of the civilized world when political and economic activity shift to the Mediterranean, where it  is destined to remain for many centuries.

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