Europeans begin the enslavement of continental natives.

Santo Domingo, Captaincy General of View → Santiago, Colony of (Spanish Jamaica) View → Cuba, Governorate of View → Castilla de Oro View → Guatemala, (Spanish Colony) View → Cuba (Spanish Colony) View → New Spain (Spanish colony) View →

Age of Discovery View → Colonization of the Americas, Spanish View → Columbian Exchange View → Aztec Empire, Spanish conquest of the View →

Strategic metals View → Slaves View →

Commerce View → Labor and Service View → Government View → Custom and Law View →