The Lithuanians suffer a crushing defeat in the Battle of Vedrosha on July 14, 1500, in which the skilled Russian commander, Prince Daniil Shchenya, employs tactics similar to those that had proved successful for the Russian army in the Battle of Kulikovo in 1380.

Vedrosha is a great victory for the Russians.

Some eight thousand Lithuanians are killed, and many more are taken prisoner, including Prince Konstanty Ostrogski, the first ever Grand Hetman of Lithuania.

The defeat is one of the reasons for the proposed Union of Mielnik between Poland and Lithuania.

After the battle, the Lithuanians lose the possibility of military initiative and restrict themselves to defensive actions.