The Peloponnese is in open revolt against the Ottomans by the end of March 1821, and by October the Greeks under Theodoros Kolokotronis have captured Tripolitsa.

The Peloponnesian revolt is quickly followed by revolts in Crete, Macedonia and Central Greece, which are soon suppressed.

Meanwhile, the makeshift Greek navy is achieving success against the Ottoman navy in the Aegean Sea and prevents Ottoman reinforcements from arriving by sea.

In 1822 and 1824 the Turks and Egyptians ravage the islands, including Chios and Psara, committing wholesale massacres of the population.