Andries de Witt (16 June 1573, Dordrecht - 26 November 1637, Dordrecht) is Grand Pensionary of Holland between 1619 and 1621.

He is the successor of Johan van Oldebarnevelt, who had been executed in 1619.

Andries de Witt is the oldest son of Johanna Heijmans and Cornelis Fransz de Witt (1545-1622), 16-fold burgomaster of Dordrecht.

He is the uncle of Cornelis de Witt and Johan de Witt, Grand Pensionary from 1652 to 1672, who are sons of his youngest brother Jacob de Witt.

Andries marries Elizabeth van den Honert in 1604, with whom he has 10 children.