Empress Go-Sakuramachi (September 23, 1740 – December 24, 1813) is the 117th monarch of Japan, according to the traditional order of succession.

Go-Sakuramachi's reign spans the years from 1762 through 1771.

This eighteenth-century sovereign is named after her father Emperor Sakuramachi and go-, translates as "later"; and thus, she could be called the "Later Sakuramachi".

The Japanese word go has also been translated to mean the "second one;" and in some older sources, this empress might be identified as "Sakuramachi II".

In the history of Japan, Go-Sakuramachi is the last of eight women to take on the role of empress regnant.

The seven female monarchs who reign before Go-Sakuramachi are Suiko, Kōgyoku (Saimei), Jitō, Genmei, Genshō, Kōken (Shōtoku), and Meishō.