Pergamon becomes independent in 262 BCE, during…
333 BCE to 190 BCE
Noted for the cleanliness of its streets and the splendor of its art, Pergamon, in west-central Anatolia, derives its extraordinary wealth from trade in pitch, parchment, and perfume, while slave labor produces a food surplus on scientifically managed state farms.
It is also a center of learning that boasts a medical school and a library second in renown only to that of Alexandria, but Pergamon is both despised and envied by the other Greek states because of its alliance with Rome.