The Old World diseases brought with the…
1516 CE to 1527 CE
The Old World diseases brought with the Spanish, against which the indigenous New World people have no resistance, are a deciding factor in the conquest; the diseases cripple armies and decimate populations before battles are even fought.
Their introduction is catastrophic in the Americas; it is estimated that ninety percent of the indigenous population is eliminated by disease within the first century of European contact.
Epidemics accidentally introduced by the Spanish include smallpox, measles and influenza.
These diseases, together with typhus and yellow fever, have a major impact on Maya populations.
Smallpox, which had been introduced into the Caribbean island of Hispaniola in 1509, enters the mainland in 1520, when Spanish settlers from Hispaniola arrive in Mexico bringing smallpox with them.
It soon spreads to the north and south.