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Giacomo Pylarini
Venetian physician and consul
Years: 1659 - 1718
Giacomo Pylarini (Jacob) (born 1659 – 1718) was a Venetian physician and consul for the republic of Venice in Smyrna who in 1701 on the children of the English ambassador to Constantinople, gave the first smallpox inoculation outside of Turkey.
This early immunization effort is called "variolation".
