Giovanni Borgia, 2nd Duke of Gandía (c.1476–1497) is the son of Pope Alexander VI, a member of the House of Borgia.

He is the brother of Cesare, Gioffre, and Lucrezia Borgia.

Giovanni, commonly known as Juan (or sometimes, Joan), is believed to be the eldest of the Pope's four children by Vannozza dei Cattanei, but this is disputed.

Due to the contents of a number of papal bulls issued after his murder, it is unclear whether Giovanni was born in 1476 or 1477.