Georg Gisze (Gisze according to the title of the Holbein painting) – born April 2, 1497 in Danzig (Gdańsk, Poland), died on February 3, 1562 in Danzig) – is a Hanse merchant.
As a member of the Hanseatic League Gisze also workd in London where he is portrayed by Hans Holbein the Younger in 1532.
After returning to his home city in 1535 he marries Christine Krüger, daughter of a prestigious citizen.
His patrician family, which includes Albrecht Gisze, bishop Tiedemann Gisze etc., had come originally from Cologne.