Antonello’s influential “Madonna and Saints” altarpiece, usually…

Antonello’s influential “Madonna and Saints” altarpiece, usually known as the “San Cassiano Altarpiece,” is painted for the Venetian church of that name (only three fragments survive).

Antonello assembles the painting’s figures symmetrically around the elevated throne of the Madonna, all placed within a large-scale architectural setting.

His sensitivity to characteristically Venetian treatments of certain themes, such as the Venetian school's preoccupation with color, light, and atmosphere, can be seen in his St. Sebastian and his Pietá, both painted in 1475-76.