Pope Clement VII, after the signing of…
August 1529 CE
Pope Clement VII, after the signing of the Treaty of Cambrai that in 1529 ends the latest Italian War between France and the Holy Roman empire, realizes that his long-term interests lie with Spain.
He signs the treaty of Barcelona with Charles in return for imperial aid in overthrowing the rebellious Florentine republic, which has continued to wage war against the empire.